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The text discusses melatonin and cannabinol (CBN) as sleep aids. It highlights that melatonin, while popular, is often over-dosed in commercial products, leading to side effects. CBN, a minor cannabinoid, is presented as a gentler alternative that supports natural sleep cycles without disrupting circadian rhythms. CBN interacts with the endocannabinoid system and is formed as THC ages. The article emphasizes CBN's mild psychoactivity and its potential for relaxation and improved sleep quality, often blended with other cannabinoids for enhanced effects. It also includes a Q&A section about CBN.

CBN: The Cannabinoid Redefining Natural Sleep Solutions

Sep 22, 2025

Chris Karazin

MG Magazine



If you’ve ever reached for a melatonin product after a long day, you aren’t
alone.

Sleep aids are big business in the wellness world, and for good reason.
According to the Centers for Disease Control, nearly one-third of adults in
the United States report getting less than the recommended seven hours of
sleep per night. The deficit drives millions of restless dreamers to try
everything from over-the-counter pills and sleepy teas to prescription
sedatives.

Proper sleep is genuinely out of reach for many people today, not just
because of trends like grind or hustle culture, but also because of real
physiological dysregulation, chronic stress, and the interference of modern
lifestyles. For thousands of years, humans have tried to understand what
happens when we sleep. While sleep science is still relatively young,
modern medicine has long advocated for a nighttime rest of seven to nine
hours in a cool, quiet environment. Sleepmaxxing, an umbrella term for a
viral TikTok trend that encompasses users sharing “sleep hacks” for
wellness, is just today’s branded version of that enduring human quest to
get the restorative rest we need.

Melatonin is a popular sleep supplement that can be effective, but it also
has downsides. Many people don’t realize the body naturally produces only
about thirty micrograms of melatonin per night. Yet, many commercial gummies
contain one to ten milligrams, which is thirty to 300 times more than our
bodies make. This massive dosing can overwhelm the body’s natural cycles,
leading to next-day grogginess, vivid dreams or nightmares, and even
dependence over time as users increase their dose and struggle to taper
off. These challenges have sparked interest in alternative natural sleep
aids like the minor cannabinoid cannabinol (CBN), which is earning a
reputation for aiding restful sleep.
What makes CBN fundamentally different?

Unlike melatonin, which tells the brain it’s time to sleep by shifting the
body’s internal clock, CBN doesn’t override the natural circadian rhythm.
Instead, it supports relaxation through different pathways in the body,
helping users unwind and fall asleep naturally without forcing the process.
CBN interacts with the body’s endocannabinoid system, which comprises
receptors that process cannabinoids found in hemp and cannabis. By binding
to the CB1 receptors in the central nervous system and CB2 receptors
throughout the body, CBN signals it’s time to relax. Rather than disrupting
the sleep cycle, it works with natural rhythms, offering a gentler, more
balanced approach to rest.

CBN is one of more than 100 cannabinoids found in cannabis and hemp plants,
but it has a unique origin story. Unlike THC or CBD, which are produced by
the plant’s biosynthesis, CBN is a product of time. The same way wine or
cheese develops a different presentation, or palate, when aged, cannabis
and hemp yield a “sleepier” effect when aged. Older, well-cured (and often
darker) cannabis tends to contain higher concentrations of CBN.

As cannabis ages — particularly if it’s exposed to heat, air, or light —
THC oxidizes and breaks down into CBN, a molecule that’s much less
psychoactive (about one-fourth as potent by most measures) but has a
fascinating set of natural effects, primarily on sleep quality. Chemically,
CBN is psychoactive, but its high is exceptionally mild, and many people
won’t notice any “buzz” at all. Instead, they may perceive more of a subtle
sense of full-body relaxation.

While there is still a long way to go with clinical research on CBN (thanks
to regulatory hurdles), animal studies and decades of consumer anecdotes
offer plenty of reasons to be excited about the substance’s sedative
effects. In early research, CBN was shown to prolong deep sleep time in
mice, especially when paired with other cannabinoids like THC.

Human consumers often report a light, gentle sense of calm. Unlike
melatonin, CBN’s effects appear more about overall physical and mental
relaxation. That difference makes CBN a favorite among people looking to
optimize, or sleepmaxx, their rest. Among those seeking the perfect night
of sweet dreams, CBN is sometimes paired with magnesium or low-dose THC to
achieve deeper, more restorative sleep.

Because CBN forms through oxidation, it’s historically been most abundant
in aged cannabis flower. But for today’s manufacturers who aim to deliver
consistent doses, CBN is produced by isolating and oxidizing THC or CBD
extracts in the lab. The result is a crystalline powder with 99.99-percent
purity. This isolate can be carefully dosed and infused into gummies,
tinctures, capsules, or vape formulations to deliver precise doses or
paired with other compounds for tailored blends.

For sleep, CBN is often blended with small amounts of THC for enhanced
sedation or with CBD for overall calm. This approach is rooted in the
entourage effect, which is the idea that cannabis compounds work better
together than on their own. Because CBN’s psychoactivity is mild, it’s seen
as more approachable for sleep than THC edibles, which sometimes cause
issues for lower-tolerance users.
CBN is good news for cannabis brands and retailers

As cannabis and hemp research expands alongside nationwide acceptance of a
new breed of wellness products, lesser-known minor cannabinoids like CBN
see increased demand. An increasing number of consumers seek targeted
wellbeing solutions that address their specific needs with as little
pharmaceutical interference as possible.

Far from a one-size-fits-all solution like over-the-counter options, CBN
offers a milder, gentler way to unwind that pairs well with other
cannabinoids, complements mindful bedtime rituals, and aligns with a
broader shift toward holistic, personalized sleep routines. CBN has earned
its spot in sleep routines and just might be the key that consumers seeking
holistic solutions have been awaiting.
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CBN and Sleep: Your Questions Answered

1. What is CBN and how does it help with sleep?

CBN (cannabinol) is a minor cannabinoid formed when THC oxidizes. It
interacts with the body’s endocannabinoid system to promote relaxation and
support natural sleep cycles without disrupting circadian rhythms.
2. How is CBN different from melatonin?

Melatonin shifts the body’s internal clock, while CBN works by
encouraging relaxation through CB1 and CB2 receptors. Many people find CBN
gentler, with fewer side effects like grogginess or vivid dreams.
3. Does CBN cause a high?

CBN is mildly psychoactive, but about one-quarter as potent as THC. Most
users don’t experience a noticeable high—just subtle relaxation that
supports better rest.
4. What kinds of products contain CBN?

Manufacturers isolate CBN into a crystalline powder and infuse it into
gummies, tinctures, capsules, or vape formulations. It’s often blended with
CBD or low-dose THC for tailored sleep support.
5. Is CBN safe to use for sleep?

While more clinical research is needed, early studies and consumer
reports suggest CBN is a safe, natural option for improving sleep quality.
As with all cannabinoids, effects may vary.

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[image: Chris Karazin founder Carolindica]

*By employing a logic-driven approach and a strong grasp of market
dynamics, Chris Karazin shaped Carolindca into one of North Carolina’s most
successful brands. Karazin founded the hemp company in 2019 after working
in outside sales for a residential solar energy firm. He is a graduate of
Appalachian State University.*

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