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A study suggests dogs on long-term CBD supplements exhibit below-average aggression but no reduction in anxiety or agitation, a finding that researchers note may be influenced by unknown dosages and owners using additional therapeutic techniques. The study also found that CBD use is higher in states with legal medical cannabis and among dogs with chronic health conditions like cancer and epilepsy, reflecting human views on the benefits of medical cannabis.

Study: Dogs Given CBD Have Below-Average Aggression  

Dec 2, 2025

TG Branfalt

Ganjapreneur

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A study published this month in the journal *Frontiers in Veterinary
Science *suggests that dogs receiving CBD supplements for an extended time
period have below-average aggression compared to dogs that are not given
CBD. The study also indicates that dogs given CBD supplements did not show
a reduction in anxiety or agitation.

The study utilized survey data from the Dog Aging Project (DAP) and
associated the change in behavior with canines that had consistently
consumed CBD for at least two years.

Dr. Julie Albright, associate professor of veterinary medicine at the
University of Tennessee and co-author of the study told UPI that the
researchers “could find that CBD preferentially affects neural circuits
related to the ‘fight’ versus ‘flight’ of the threat or stress response
pathway” but that the study’s design “did not allow for detailed responses
about the CBD use from the dog owners,” meaning the products given to the
dogs, including the dosage, is unknown.

“For example, the risk that aggressive dogs pose may have prompted their
owners to implement many therapeutic techniques, such as professional
behavior modification and strong avoidance of triggers, compared to owners
of dogs displaying fear without aggression. This multimodal treatment
approach may have contributed to better outcomes for aggressive dogs
compared to the other types of non-aggressive behavior problems.” —
Albright to UPI

The study also found that CBD use among canines tended to be higher in
states with legalized medical cannabis. Dogs with dementia, osteoarthritis,
cancer, epilepsy, hip dysplasia, clinical sign–based gastrointestinal
disorders, and chronic diarrhea were more likely to use CBD compared to
dogs without those conditions.

Maxwell C. K. Leung, assistant professor of pharmacology and toxicology and
cannabis researcher at Arizona State University, and a study co-author,
told UPI that the higher CBD use rates among dogs in states with medical
cannabis access demonstrate how “we humans view medical cannabis and
cannabidiol as beneficial to humans and dogs alike.”

“Medical cannabis is used for a number of human health conditions, such as
osteoarthritis and epilepsy,” he said. “Dogs also have similar health
conditions, and we give CBD to our animals for the same reasons. I think
this is an example of how we treat our companion animals as members of our
family.”

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