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A top conservative organization, the Koch-founded Americans for Prosperity Foundation (AFPF), is backing a coalition of marijuana businesses urging the U.S. Supreme Court to hear a case challenging federal cannabis prohibition. AFPF argues that the Controlled Substances Act (CSA), as applied to intrastate marijuana activity in legal states like Massachusetts, exceeds constitutional limits on federal authority and violates the Commerce Clause and principles of federalism.

Top Conservative Group Urges Supreme Court To Take Marijuana Case Challenging Federal Prohibition

Nov 20, 2025

Kyle Jaeger

Marijuana Moment



A top conservative advocacy organization is backing a coalition of
marijuana businesses that are asking the U.S. Supreme Court to take up a
case challenging the constitutionality of federal cannabis prohibition.

In an amicus brief filed with the court on Wednesday, the Koch-founded
Americans for Prosperity Foundation (AFPF) implored justices to hear the
case and settle the question of whether imposing federal marijuana
criminalization within states that have enacted their own legalization laws
violates the Commerce Clause of the U.S. Constitution.

The libertarian-leaning AFPF said in the brief that it’s their
organization’s belief that “the general power of governing rests with the
States—not the federal government—and that most decisions should be made at
the state and local levels, reflecting the needs and priorities of their
communities.”

To that end, it said, the Controlled Substances Act (CSA) that treats
cannabis as a strictly prohibited Schedule I drug—at least as it concerns
the Massachusetts-based marijuana businesses petitioning the court—”exceeds
constitutional limits on federal authority as an original matter and cannot
be squared with basic principles of federalism.”

“More broadly, AFPF believes that *Gonzales v. Raich*—a constitutional
aberration granting the federal government authority to trample on States’
core power to choose whether and how to regulate local private conduct—was
wrongly decided and should be squarely overruled,” it said.

In* Gonzales v. Raich*, a landmark 2005 case, the Supreme Court narrowly
determined that the federal government could enforce prohibition against
cannabis cultivation that took place wholly within California based on
Congress’s authority to regulate interstate commerce.

The new case “is not about sound public policy or the wisdom of
Massachusetts’ regulatory choices. The core question here is whether the
federal government may trespass on and override exercises of States’
traditional police power to regulate purely local activity and decide for
themselves how best to protect the health, safety, and welfare of their
residents,” AFPF said. “Under our system of federalism, the answer is no.”

“As applied to Petitioners—which ‘cultivate, manufacture, possess, and/or
distribute marijuana wholly within Massachusetts in full compliance with
its laws and regulations,’—the CSA is an affront to our system of
federalism. It federally criminalizes wholly intrastate activity not
intended for and without any empirically demonstrable link to interstate
commerce. This assertion of general police power is unconstitutional.”

AFPF—supporting the petitioners Canna Provisions, Gyasi Sellers, Wiseacre
Farm and Verano Holdings—said justices should “sweep *Raich* into the
dustbin and squarely overrule it.”

“The Petition presents an ideal (and rare) opportunity to begin to ‘temper’
and ‘modify,’ this Court’s Commerce Clause and Necessary and Proper Clause
jurisprudence to bring it closer in line with the Constitution’s original
public meaning. This Court should take up that task. This Court should end
*Raich’s* ‘rational basis’ error by squarely overruling that aberration and
making clear that the Constitution requires more before the federal
government may intrude on the core police powers it reserves to the States.
As Petitioners explain, the sky will not fall if this Court takes that
modest step. On the contrary, our constitutional republic will be healthier
for it.”

The powerhouse law firm Boies Schiller Flexner LLP last month submitted
their petition for writ of certiorari from the court on behalf of their
clients, and the Justice Department last week declined the opportunity to
file a brief for or against the case’s consideration by the justices.

A lead attorney representing the petitioners recently told Marijuana Moment
that he’s “hopeful”—albeit somewhat “nervous”—about the prospect of
justices ultimately taking up the matter and deciding to address the key
legal question about the constitutionality of federal cannabis prohibition.

“Time is of the essence,” Josh Schiller said, noting the dramatic shift in
public opinion and state laws governing cannabis. “We think that this is
the right time for this case because of the need—the industry needs to get
relief from federal oversight at the moment.”

A U.S. appeals court rejected the arguments of the state-legal cannabis
companies the firm is representing in May. It was one the latest blows to
the high-profile lawsuit following a lower court’s dismissal of the claims.
But it’s widely understood that the plaintiffs’ legal team has long
intended the matter to end up before the nine high court justices.

Four justices must vote to accept the petition for cert in order for the
court to take up the case. The next step would have been for the Department
of Justice to file its initial brief, which had a due date of November 28.
It remains to be seen if the court will end up requesting a brief from the
government now that it has declined to do so on its own accord.

While it is not clear if SCOTUS will ultimately take the case, one sign
that at least some on court might be interested in the appeal is a 2021
statement from Justice Clarence Thomas, issued as the court denied review
of a separate dispute involving a Colorado medical marijuana dispensary.

Thomas’s comments at the time seemed to suggest it’d be appropriate revisit
*Raich*—a move that could upend federal prohibition.

The statement pointed to policy developments since the earlier case was
decided, such as the hands-off enforcement approach taken by the Department
of Justice as more states legalized cannabis and a congressional budget
rider protecting state-legal medical marijuana programs.

“Whatever the merits of *Raich* when it was decided, federal policies of
the past 16 years have greatly undermined its reasoning,” Thomas wrote,
describing the government’s approach to cannabis enforcement as “a half-in,
half-out regime that simultaneously tolerates and forbids local use of
marijuana.”

“Though federal law still flatly forbids the intrastate possession,
cultivation, or distribution of marijuana…the Government, post-*Raich*, has
sent mixed signals on its views,” the justice continued, saying the
situation “strains basic principles of federalism and conceals traps for
the unwary.”

The initial complaint in the current case now known as *Canna Provisions v.
Bondi*, filed in U.S. District Court for the District of Massachusetts,
argued that government’s ongoing prohibition on marijuana under the CSA was
unconstitutional because Congress in recent decades had “dropped any
assumption that federal control of state-regulated marijuana is necessary.”


*— Marijuana Moment is tracking hundreds of cannabis, psychedelics and drug
policy bills in state legislatures and Congress this year. Patreon
supporters pledging at least $25/month get access to our interactive maps,
charts and hearing calendar so they don’t miss any developments.*


*Learn more about our marijuana bill tracker and become a supporter on
Patreon to get access. —*

At oral arguments on appeal late last year, David Boies told judges that
under the Constitution, Congress can only regulate commercial activity
within a state—in this case, around marijuana—if the failure to regulate
that in-state activity “would substantially interfere [with] or undermine
legitimate congressional regulation of *inter*state commerce.”

Boies, chairman of the firm, has a long list of prior clients that includes
the Justice Department, former Vice President Al Gore and the plaintiffs in
a case that led to the invalidation of California’s ban on same-sex
marriage, among others.

Judges, however, said they were “unpersuaded,” ruling in an opinion that
“the CSA remains fully intact as to the regulation of the commercial
activity involving marijuana for non-medical purposes, which is the
activity in which the appellants, by their own account, are engaged.”

The district court, meanwhile, said in the case that while there are
“persuasive reasons for a reexamination” of the current scheduling of
cannabis, its hands were effectively tied by past U.S. Supreme Court
precedent in *Raich*.

This comes in the background of a pending marijuana rescheduling decision
from the Trump administration. President Donald Trump said in late August
that he’d make a determination about moving cannabis to Schedule III of the
CSA within weeks, but he’s yet to act.

Meanwhile, last month the Supreme Court agreed to hear a separate case on
the constitutionality of a federal law prohibiting people who use marijuana or
other drugs from buying or possessing firearms. The Trump administration
has argued that the policy “targets a category of persons who pose a clear
danger of misusing firearm” and should be upheld.

The post Top Conservative Group Urges Supreme Court To Take Marijuana Case
Challenging Federal Prohibition appeared first on Marijuana Moment.

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