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5 Simple Ways to Boost Your Endocannabinoid System Without Cannabis
Oct 15, 2025
Dragonfly de la Luz
Cannabis Now
Our bodies all have a network of cannabinoid receptors that is vital to the
health of all mammals: the endocannabinoid system. The ECS is a vast
network of chemical compounds and receptors (namely CB1 and CB2) that
regulate our most basic functions – sleep, appetite, mood, the immune
system, inflammatory response, aging and memory. Endocannabinoids even
produce feelings of relaxation and euphoria similar to those which come
from ingesting cannabis.
Aside from regulating essential everyday functions, the ECS maintains the
body’s homeostasis down to the cell level by reversing damage in whatever
way necessary. In cancer patients, for instance, cancer cells can be
programmed to kill themselves when endocannabinoid levels increase.
[image: boosting endocannabinoid system with omega 3s leafy greens no
alcohol exercize]
But as with most things, balance within this system is key. An overly
inhibited CB1 receptor may lead to moodiness, depression and a suppressed
immune system. On the other hand, an over-activated CB1 can increase risk
of psychoactivity, inflammation, diabetes, obesity and cardiovascular
problems. One study found that a highly sensitive endocannabinoid system is
linked to almost all chronic diseases. So, a balanced ECS is fundamental to
good health.
Consuming cannabis is one fun and easy way to optimize the ECS. But not
everyone has the freedom to enjoy this medicinal plant. Here are our top
five simple ways to boost the endocannabinoid system without the aid of
marijuana.
* Drink Less Alcohol*
Martin Lee, director of Project CBD and author of “Smoke Signals: A Social
History of Marijuana – Medical, Recreational and Scientific,” explained the
problem with drinking:
“Alcohol is a poison that causes an acute stress response upon occasional
consumption, which, in turn, provokes a temporary uptick of endocannabinoid
activity as a protective response against stress,” Lee said. He added that
while occasional drinking probably wouldn’t harm the ECS, “chronic
alcoholism has the opposite effect, resulting in a depletion of
endocannabinoid tone due to the wear and tear of too much stress. A low
endocannabinoid baseline level makes a person more vulnerable to disease.”
* Get Bodywork Treatments*
A study by Auckland’s Unitec Institute of Technology showed that levels of
anandamide — a cannabinoid responsible for feelings of bliss and joy —
more than doubled after patients received osteopathic manipulative medicine
treatments. This therapy can take various forms, including chiropractic,
physical therapy and massage. Even acupuncture has a positive effect on the
endocannabinoid system, so there’s never been a better excuse to take a spa
day.
* Eat Leafy Greens*
If smoking frosty greens is not an option, then eating leafy greens will
suffice. Along with oregano and black pepper, leafy greens contain
beta-caryophyllene, a terpene that activates the CB2 receptor and is
believed to have high potential for combatting inflammatory conditions and
autoimmune disorders.
* Eat More Omega-3s*
Omega-3 fatty acids are essential for a well functioning ECS. Some
scientists say that without them, CB1 receptors may not form correctly,
which could lead to “impaired emotional behavior.” While fish oils are
widely considered one of the best sources of omega-3s, hemp is an excellent
alternative. Whether in seed, oil or protein form, hemp’s omega-3s can help
keep your ECS functioning properly.
* Exercise *
German researchers have shown that “runner’s high” is not actually caused
by an endorphin rush, but instead is a result of an increase in
endocannabinoid production. And running isn’t the only activity that
produces this effect. Any exercise can lead to an increase in
endocannabinoids, so long as the activity doesn’t feel forced. The body
interprets forced exercise as a stressor, which can actually produce the
opposite effect and decrease endocannabinoid receptor signaling. So, dust
off the yoga mat, jump up and down on a trampoline or even go out dancing
to maintain a healthy endocannabinoid system.
*Originally published in the print edition of Cannabis Now.* *LEARN MORE*
*TELL US, *how do you combine cannabis with other wellness techniques?
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